Secondary Dataset Analyses in Heart, Lung, and Blood Diseases and Sleep Disorders (R21)

Posted on: December 10, 2013

The purpose of this funding opportunity is to stimulate well-focused secondary analyses using existing human datasets to test innovative hypotheses concerning the epidemiology, pathophysiology, prevention or treatment of diseases/conditions relevant to the NHLBI mission. Analyzing existing datasets in novel ways provides a cost-effective method to address research questions and generate preliminary data for subsequent research proposals.

Through a variety of mechanisms, the NHLBI supports clinical research to better clarify development, progression, prevention, and treatment of cardiovascular, pulmonary, blood, and sleep disorders. Typically, large clinical trials and epidemiologic research studies generate data with potential utility beyond the specific hypotheses and questions for which they were designed. Often these data elements are not fully utilized, especially when new research questions emerge after the project's funding has ended. The goal of this initiative is to support early-stage exploratory studies through analyses of existing datasets. This program will enable investigators to pursue innovative projects for which preliminary data are limited, and assist in demonstrating concept validity expected in NIH research project (R01) review.

Due dates:

February 20, 2013; February 20, 2014; February 20, 2015; February 19, 2016 , by 5:00 PM local time of applicant organization.

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